Abstract For the determination of Nickel (II), a straight forward, sensitive, and accurate spectrophotometric approach has been created. The reagent 2-Acetylpyridine semicarbazone (APS) react with nickel (II) in aqueous solution in the pH range 0.5-12. In the pH range of 8.0 to 10.0, 2-Acetylpyridine semicarbazone (APS) interacts with nickel (II) to produce a light yellow […]

Abstract The goal of this study was to compile the most recent research, with a particular focus on a logical approach to topical formulation and the fundamental components of topical drug delivery systems. Topical medication applications offer the benefit of delivering the drug directly to the site of action and acting for a longer time. […]

Abstract Force degradation studies or stress testing are commonly employed in pharmaceutical industries in order to develop a stability indicating method (SIM). In forced degradation studies, drug substance (API) or a drug product is subjected to various extremities of pH, humidity, hydrolysis and oxidation, photolytic and thermal conditions which in turn produce various degrading products […]

Abstract The aim of present review article is to focus light on process validation and its basic concepts in pharmaceutical industry. Validation is a key aspect of Quality system. Prime requirement of quality is that everything should be validated (process, system, equipment etc.). “Process validation is establishing documented evidence which provides a high degree of […]

Abstract The reported toxicities of antitrypanosomal drugs and the emergence of drug resistant trypanosomes underscore the need for the development of new antitrypanosomal agents. We report herein the synthesis of phenolic acid derivatives (vanillic acid and para-hydroxybenzoic acid) and their antitrypanosomal potential against Trypanosoma congolense. The compounds were synthesized by oxidizing the aldehyde functional groups […]

Abstract Oral drug administration is also the favored method of drug administration. GRDDSs are a novel approach in the Pharmaceutical Industry (Gastroretentive Drug Delivery System). Dosage forms that can be retained in the stomach are called GRDDs. By continually releasing the drug for a long period of time until it reaches its absorption site, GRDDSs […]

Abstract Nephropathy of pregnancy in the body accumulate fluid (edema) in which the capillaries are losing properties of detention of the fluid, resulting in easy absorption of all the liquid in the tissue. Nefhropathia is dangerously for feminine health. Keywords Nefhropathia, praeeclampsia, eclampsia, condition, fruit, water, hypertension, become pregnant, urine, treatment. Google Scholar Citation [Full […]

Abstract Theatrical fog is produced by a fog-machine which vaporizes a propylene glycol and water mixture (fog liquid). On leaving the machine and mixing with the cool external air, the vapor condenses and forms a dense fog. This fog finds application in the professional entertainment industry, fire service, armed forces and in churches for different […]

Abstract The increasing use of propylene glycol based theatrical fog at events in Nigeria has necessitated an evaluation of its potential toxicity. Propylene glycol based fog finds application in the professional entertainment industry, fire service, armed forces and in churches for different purposes. Therefore, this inhalational toxicological study investigated the potential health effects of theatrical […]

Abstract Fungal is a deadly infection and kills many people annually. There is a need for new antifungal agents due to the emergence of drug resistant fungal infections. In this report we describe the pseudosaccharin amine derivatives with antifungal activities against Candida albicans and A. fumigatus. Compound 4g showed MIC of 7 and 25 µg/mL […]