Protective Effect of Silibinin during Cerebral Ischemia is correlated with Altering Oxidative Stress, Transition Metal, and Antioxidant

Abstract Cerebral ischemia may elevate oxidative stress due to a large amount of the generated reactive oxygen species.Silibinin is an active component of flavonoids possessing anti-inflammatory and anti-oxidative properties.Transition metal of iron (Fe), copper (Cu), and antioxidant of superoxide dismutase (SOD) and catalase (CAT) are required for the brain functions. This study was to elucidate […]

Comparative Study of the Nutritional and Anti Nutritional Composition of Phyllantus niruri and Carica papaya

Abstract The leaves of Phyllanthus niruri and Carica papaya were dried and ground for antimicrobial and physiological properties. The data generated were subjected to basic statistical analysis with both samples having low levels of oxalate (1.05 mg/100g) for Phyllanthus niruri and (1.06mg/100g) for Carica papaya, but high in phytate, glycoside, and steroids. The proximate analysis […]

Danta Wood Saw Dust Characterizations for Pyrolysis Oil Production potentials

Abstract Researchers led by rise in energy demands, exhausting fossil fuel resources and consequent environmental management problems, are in search for solution, in recent times. Fast pyrolysis process has commanded most intensive interest for solving the above research problems amongst other alternative fuel technologies. In this present work, DWSD feedstock characterization was carried out via […]

Synthesis, Characterization and Anticancer activity of fused Pyrazolo Pyrimido benzothiazoles

Abstract The compound 3-amino- 4-imino 6, 9 dimethyl- pyrazolo-[3, 4-e] pyrimido [2, 3-b] [1, 3] benzothiazole(IV) was obtained by the reaction of 3-Cyano -6, 9-dimethyl -2-methylthio -4-imino -4H-pyrimido [2, 1-b] [1, 3] benzothiazole (III) with Hydrazine hydrate (80%) in presence of anhydrous K2CO3 in DMF as solvent, and screened their in-vitro anticancer activity by the […]

Health Behavioral Attitudes, Awareness and Risk of Osteoporosis in Individuals Working at the University

Abstract Aim of study was to determine awareness and risk of osteoporosis (OP) in working individuals. Materials Methods: cross-sectional research, sample selection in the survey application, consists of the staff of one üniversity Turkey province between October and December 2018. 125 volunteer were participate in study. Socio-demografic questions, One-minute OP risk test was applied. Mean, […]

Research Progress of Phosphorylated Polysaccharides

Abstract Phosphorylated polysaccharides, as a very important polysaccharide, exist widely in animals, plants and microorganisms. It has a variety of biological activities such as antioxidant, immune, anti-tumor and anti-viral. According to the research, its therapeutic effect is significant, but it is not easy to extract natural phosphorylated polysaccharides, so the artificial synthesis of phosphorylated polysaccharides […]

The Role of Cellular Immunity in Formation of Endothelium Disfunction in Patients with Nonspecific Aortoarteriitis

Abstract The investigation of the cellular immunity disorders and its correlation with endothelial disfunction in the patients with nonspecific aortoarteriitis are discussed in the article. It was found out direct correlation between contanse of the CD4+, CD8+, CD20+, CD25+, CD95+ and HLA-DR, endothelinum-1 and circulating endotheliocites levels and indirect correlation between the cellular immunity changers […]

Partition and Evaluation of Crude Methanol Seed Extract of Picralima nitida (Stapf.) T. Durand and H. Durand (Apocynaceae) for Larvicidal Activity on Aedesaegypti Larvae

Abstract In this study the active crude methanol seed extract of pricralimanitida was partition and evaluated for larvicidal activity against Aedes aegypti. About 50g of the active crude methanol extract was dissolve in sufficient quantity of water. This was extracted with sufficient quantity of n-hexane exhaustively; after this it was also exhaustively extracted with sufficient […]

Regulative Influence of Propolis on Oxidative Stress and Hormonal Changes in Chronic Unpredictable Mild Stress-induced Depression Model of Rats

Abstract In Depression is an epidemic disease of today’s life and, is one of the most important social problems that increases each year. Chronic stress-depression causes increased lipid peroxidation, release of free radicals, and hormonal imbalance. The protective properties of propolis, known as an antioxidant, on chronic unpredictable mild stress (CUMS) and its toxic effect […]

Quality Assurance and Comparative Studies of Different Brands of Pregabalin in Nigerian Pharmacies

Abstract Pregabalin, a neuropsychotropic agent, is a drug of choice for the treatment of epilepsy and neuropathic pain. Several brands are available in the Nigerian drug market which raises the challenge of determining the products that could be interchanged with the innovator brand or with other generics.  Therefore, the current study was carried out to […]