Abstract Oral drug administration is also the favored method of drug administration. GRDDSs are a novel approach in the Pharmaceutical Industry (Gastroretentive Drug Delivery System). Dosage forms that can be retained in the stomach are called GRDDs. By continually releasing the drug for a long period of time until it reaches its absorption site, GRDDSs can enhance the regulated release of drugs with an absorption window. GRDDS are thus favourable for such drugs by improving their bioavailability, therapeutic effectiveness, and the possibility of dose reduction, as well as improving drug solubility, which is less soluble in a high pH setting. In this review, Gastroretentive Drug Delivery System of antihypertensive is discussed.
Keywords Gastroretentive Drug Delivery System, Floating, Antihypertensive, GRDDS, FDDS.