Abstract Fungal is a deadly infection and kills many people annually. There is a need for new antifungal agents due to the emergence of drug resistant fungal infections. In this report we describe the pseudosaccharin amine derivatives with antifungal activities against Candida albicans and A. fumigatus. Compound 4g showed MIC of 7 and 25 µg/mL against Candida albicans and A. fumigatus respectively.
Keywords Antifungal, Azole, Minimum Inhibitory Concentration, Pseudosaccharin amine.