Abstract The goal of this study was to compile the most recent research, with a particular focus on a logical approach to topical formulation and the fundamental components of topical drug delivery systems. Topical medication applications offer the benefit of delivering the drug directly to the site of action and acting for a longer time. The main route of topical medication delivery is through the skin, which is one of the most common and easily accessible organs on the human body for topical administration. Many commonly used topical treatments, such as ointments, creams, and lotions, have a number of drawbacks, such as being sticky and making the patient uncomfortable when administered. Furthermore, they have a lower spreading coefficient and must be applied by rubbing, as well as having a difficulty with stability. As a result of all of these characteristics, the use of gel has risen in both cosmetics and medicinal preparations. A gel is a colloid that is 99 percent liquid by weight and is immobilised by surface tension between it and a macromolecular network of fibres formed by a little quantity of gelatinous material.
Keywords Pharmaceutical gels; Terminologies; Characteristics; Classification; Preparation; Evaluation of Gels.