Category: Uncategorized

Cosmetic Product: A Review on Lipstick

Abstract Lipsticks formulations are used to the enhancement of the beauty of the lips these are the cosmetic product which contains pigments, oil, waxes, an emollients that apply the color an protection to the lips. This review was conducted to examine information about the history of Lipsticks; ingredients used to in the preparation of Lipsticks […]

Method development and validation of RP-HPLC method in tablet dosage form: A Review

Abstract HPLC is the dominant separation technique for drug detection, separation and quantification. To optimize the method, a number of chromatographic parameters were analyzed, such as sample pre-treatment, selection of mobile phase, columns, detector selection. The aim of this article is to review the development, optimization and validation of the method. HPLC method development depends […]

A review on analytical method development and validation of novel HPLC technique in pharmaceutical dosage form

Abstract Chromatography is primarily a separation technique, but it is primarily used in chemical analysis. High-performance liquid chromatography (HPLC) is a highly versatile technique that separates analytes by passing them through a column packed with micron-sized particles. Today, reversed-phase chromatography is the most commonly used separation technique in HPLC. Reasons include the reversed-phase method’s simplicity, versatility, and applicability. This is because the reversed-phase method can handle compounds of different polarities and molecular weights. Reversed-phase chromatography is used for both analytical and preparative applications in the field of biochemical separation and […]

Applications of Nanoparticles for Drug Delivery in Cancer Treatment: A Review

Abstract Anticancer drug resistance virtually always arises and poses major hindrances on the way to curative treatment of numerous human malignancies. Numerous cancer patients have hopeful response to 1st line chemotherapy but end up with cancer advancement or cancer relapse, which needs additional management. Response to consequent chemotherapy using different agents typically decreases considerably because […]

Study of antimicrobial activity from plant extracts of Grewia abutilifolia

Abstract Grewia abutilifolia is a threatened medicinal plant having immense unexplored therapeutic activities. Four different types of extracts (Ethanolic extract, Petroleum ether soluble fraction, Chloroform soluble fraction and aqueous soluble fraction) of Grewia abutilifolia plantwere prepared and evaluated for Preliminary phytochemical constituents. All the extracts were screened for antimicrobial activity against Bacillus cereus, Staphylococcus aureus, […]

Stability Testing of Ayurvedic Drugs: An Indian Regulatory Perspective

Abstract The safety and effectiveness of a product are greatly influenced by its stability. Ayurvedic, Siddha, and Unani (ASU) medicine includes single-herb or polyherbal formulations with or without mineral medications and/or drug ingredients derived from animals. Pharmaceutical products have currently undergoing stability testing in accordance with the guidelines of the International Conference on Harmonisation of […]

Synthesis and Characterization of 3-Cyano- 9,12-Dimethyl -4,14-Dioxo-2Methylthio-Pyrimido[2,3-b] Pyrazolo[3,4-e] Pyrimido[2,3b][1,3]Benzothiazole and its 2-Substituted Derivatives

Abstract A novel fused heterocyclic compound 3-cyano- 9, 12-dimethyl -4, 14-dioxo- 2-methylthio- Pyrimido[2,3b] Pyrazolo[3,4-e] Pyrimido[2,3-b][1,3] Benzothiazole (3) was prepared by the reaction of 3-amino – 6, 9-dimethyl- 4-oxo pyrazolo[3,4-e]-pyrimido[2,1-b][1,3] benzothiazole (1) with Ethyl-2-cyano-3,3’-bis-methylthio acrylate (2)in presence of anhydrous K2CO3 in DMF.Moreover the compound (3) has thiomethyl functionality at 2- position act as best leaving group, […]