Abstract A novel fused heterocyclic compound 3-cyano- 9, 12-dimethyl -4, 14-dioxo- 2-methylthio- Pyrimido[2,3b] Pyrazolo[3,4-e] Pyrimido[2,3-b][1,3] Benzothiazole (3) was prepared by the reaction of 3-amino – 6, 9-dimethyl- 4-oxo pyrazolo[3,4-e]-pyrimido[2,1-b][1,3] benzothiazole (1) with Ethyl-2-cyano-3,3’-bis-methylthio acrylate (2)in presence of anhydrous K2CO3 in DMF.Moreover the compound (3) has thiomethyl functionality at 2- position act as best leaving group, which was get substituted different selected nucleophile like, p-chloro phenol, p-Toludine and pyrrolidine givesits 2-substituted derivatives (4a-c).
Keywords K2CO3, DMF, 2-amino- 4,7- dimethyl [1, 3] benzothiazole, Pyrimido Pyrazolo Pyrimido Benzothiazole.