Abstract The aim of the present study was to investigate the proliposome as potential carriers for efficient oral delivery of GIibenclamide in order to improve its bioavailability. The Glibenclamide loaded proliposomes were prepared using hydrogenated soyphosphatidylcholine (HSPC), cholesterol and using sorbitol as the carrier in varying ratios and characterized for entrapment efficiency, vesicle size, The […]

Abstract Glycogen storage disease type IV (GSD-IV) “Andersen’s disease” is an autosomal recessive disorder due to a deficiency of glycogen branching enzyme (GBE). We report a four years old female patient with glycogen storage disease type-IV who exhibited an abdominal distension and failure to thrive since the age of 9 months. The patient showed hepatosplenomegaly […]

Abstract The genus Deguelia comprises the American species previously included in Derris Lour. Millettia Wight & Arn. and Lonchocarpus subg. Phacelanthus Pittier. Considering the need of systematic definition to the genera Derris, Deguelia and Lonchocarpus, and also the economic importance presented by several species within these genera, which produces rotenone or deguelin (natural insecticides widely […]

Abstract In this study, the locally available materials which include; montmorillonite clay and rice husks were used to synthesize montmorillonite-silica nanocomposite as adsorbent in removal of lead from aqueous solution. Fourier transform infra-red (FTIR), was used to characterize the adsorbent. Batch method of adsorption was employed in the study and parameters that influence the adsorption […]

Abstract A greenhouse study was carried out at Cocoa Research Institute of Nigeria (CRIN), Ibadan to investigate   growth factors, dry matter yield and P-uptake of cashew seedlings of different nut sizes using organo-mineral and inorganic fertilizers. The fertilizers were applied at rates of 0, 10, 20 ton/ha and 0, 10, 20kg N/ha for seven treatments […]

Abstract Review main postulates of industrial safety applied to activities of high risk in the industry. Security is fundamental in the processes of each company even more for those who handle high risk tasks, since this way will preserve the safety of workers, this article focuses on this issue as it is important to maintain […]

Abstract Many people have suffered from hypertension and comorbid diseases for long years. Before the discovery of antihypertensive drugs, plants were used in folk medicine to treat hypertension. Nowadays, sufferers still prefer medical plants versus drugs. Furthermore, researchers focus on herbal drugs. There are lots of researches about plants which are used for cardiovascular diseases […]

Abstract Introduction and Objective: Morphine is one of the most important alkaloids of the opioid family and its most effective compound. Morphine is a very potent analgesic and narcotic drug. Considering the widespread use of morphine and its derivatives, its effects on hormones, especially sex hormones, are very important. The aim of this study was […]

Abstract The objective of this study is to determine the antioxidant activity and phytochemical constituents of methanol extract of five medicinal plants. Preliminary phytochemical screening was determined using modified method of Harbone while quantitative phytochemical test was carried out using HPLC technique method of AOAC. Preliminary phytochemical screening revealed the presence of flavonoids, phenols alkaloids, […]

Abstract The immunomodulatory effect of the ethanolic leaf extract of Phyllantus amarus on wistar rats was investigated. Twenty eight (28) male animals were used for the study. The animals were divided into four (4) groups of seven (7) animals each. Group 1 was the normal control and received distilled water, animals in group 2 were […]