Abstract Paracetamol (PCM) is widely used as analgesic and antipyretic drug, but at high dose it leads to undesirable side effects, such as hepatotoxicity. This study gives the information about hepatoprotective activity of Celastrus paniculatus leaves extract against paracetamol and ethanol induced hepatotoxicity. PCM induced hepatotoxicity was evaluated by an increase (P<0.05) in serum aspartate […]

Abstract In this study the operation of was administered studying the antiulcer results orally. Toxicity experiments on albino rats over a period indicate no morality at a dose of 2000mg/kg Duration: 14 days. In the rats no significant was seen during the study. This assist in predicting this It contains no toxicity whatsoever, and is […]

Abstract Background/objectives: Health related problems of geriatrics require special attention because these people face many problems, associated to health, social support and economic uncertainty. The study aims to evaluate effectiveness of pharmaceutical care programme on health outcome of geriatric patients by identifying the drug related problem, comparing the medication adherence, and quality of life and […]

Abstract Coriandrum sativum L. seed oil was studied by GC-MS. The oil was also screened for antimicrobial activity. Fourty five components were detected by GC-MS analysis. The alcohols constituted the major bulk of the oil (62.94%), followed by terpenoids (12.87%), aldehydes (10.21%), hydrocarbons (6.34%), ketones (5.93%) and others (0.81%). The antibacterial activity of the oil […]

Abstract A novel coumarin derivative has been isolated from the dichloromethylene fraction of the aerial part of the Sida rhombifolia. The structure of the isolated compound has been established as 7-hydroxy-6-methoxy coumarin based on the spectral (UV, IR, 1HNMR, 13CNMR, mass) data. Keywords Sida rhombifolia, Malvaceae, 7-hydroxy-6-methoxycoumarin. Google Scholar Citation [Full Text: PDF]

Abstract Lepidium sativum L. is an annual fast-growing edible plant in the family Brassicaceae. This plant is a key element in African traditional system of medicine. This herb has many health promoting properties including: hypoglycemic, antioxidant, antimicrobial, antiosteoporotic, antiasthmatic and diuretic properties [1]. The GC-MS analysis of Lepidium sativum oil revealed the presence of twenty […]

Abstract In order to develop a chemical approach to analyze opto-electronic and biological properties of the coumarin scaffold, we focused on the synthesis library of new coumarin analogues. Starting from salicylic aldehyde derivatives, the coumarin scaffold was constructed and functionalized via selective iodination, Knoevenagel condensation and Sonogashira coupling. Our library model proposes the functionalization of […]

Abstract This study was designed to investigate the constituents and antimicrobial activity of Croton cordofana oil. The genus Croton comprise a diverse group of plants including trees, herbs and shrubs. Croton species are used against a wide array of diseases including cancer, diabetes, dysentery, worms, ulcers, inflammations and weight loss. GC- MS analysis of Croton […]

Abstract Guiera senegalensis is a shrub (3-5m in height) found mainly in west Africa.Literature reports revealed several traditional uses for this plant.It is used against fever, respiratory congestion , cough, lung disorders and malaria. GC- MS analysis of Guiera senegalensis oil revealed the presence of the following major components: i)-9,12-octadecadienoic acid (Z,Z)-, methyl ester (23.77%). […]

Abstract The present study deals with transition metal complexes of an O,O-chelating ligand possessing amide moity. The Ligand 2-Hydroxypyridine-3-carboxamide(L) and its new mononuclear complexes [M(H2O]2L2]Cl2 with Co(II), Ni(II) and Cu(II) have been prepared using  microwave assisted synthesis, an environmentally benign method of synthesis.  The ligand and the metal complexes have been characterized by elemental analyses, […]