Abstract The present study deals with transition metal complexes of an O,O-chelating ligand possessing amide moity. The Ligand 2-Hydroxypyridine-3-carboxamide(L) and its new mononuclear complexes [M(H2O]2L2]Cl2 with Co(II), Ni(II) and Cu(II) have been prepared using microwave assisted synthesis, an environmentally benign method of synthesis. The ligand and the metal complexes have been characterized by elemental analyses, magnetic susceptibility measurements and spectroscopic methods like Fourier Transform-Infrared spectroscopy and UV-visible spectroscopy. The ligand and metal complexes were screened against Escherichia coli, Staphylococcus aureus and Bacillus subtilis.
Keywords Environmentally Benign Synthesis,Bioactive Ligands, 2-Hydroxypyridine-3-carboxamide, Microwave Assisted Synthesis, Biological evolution.