Abstract Guiera senegalensis is a shrub (3-5m in height) found mainly in west Africa.Literature reports revealed several traditional uses for this plant.It is used against fever, respiratory congestion , cough, lung disorders and malaria. GC- MS analysis of Guiera senegalensis oil revealed the presence of the following major components: i)-9,12-octadecadienoic acid (Z,Z)-, methyl ester (23.77%). ii)- hexadecanoic acid, methyl ester (22.92%) , iii- 9-octadecenoic acid methyl ester (21.14%) and iv)- methyl stearate (12.27%). Guiera senegalensis oil was assessed for antimicrobial activity against five standard microorganisms. The oil showed moderate activity against Staphylococcus aureus beside weak activity against other test organisms.
Keywords Guiera senegalensis, Oil, GC-MS Analysis, Antimicrobial Activity.