Abstract 3-Dichloromethyl-1,2,2-trimethylcyclopentanecarboxylic acid is used in the synthesis of biologically active substances with a trimethylcyclopentane moiety. The procedure of obtaining of the aforementioned acid has been optimized using mathematical planning of the experiment. The reaction conditions and the amounts of reagents are determined. As a result, technique was simplified, and its duration was decreased.
Keywords 3-dichloromethyl-1,2,2-trimethylcyclopentanecarboxylic acid, methods of mathematical design, synthesis.