Abstract This study aimed to evaluate the inhibitory effects of water-soluble uronans (the low-molecular-weight analogues of alginic acids) isolated from Alaria fistulosa on ROS generation and MMP-1 expression in vitro using an immortalized human keratinocyte cell line. HaCaT cells were pretreated with A. fistulosa uronans (0.1, 1 and 10 μg/ml, respectively) prior to UVB irradiation […]

Abstract NMR relaxometry proved to be a powerful tool that provides useful information on the molecular dynamics of different pharmaceutical materials. The proton NMR relaxometry was measured using low-field NMR equipment. The aim of this work was to evaluate the interaction of different drugs in pharmaceutical systems, such as: propranolol (POP) and atorvastatin (ATV) in […]

Abstract An acquaintance of the deliberation of sodium, potassium, and calcium in the blood is essential in association with a variety of problems. There are about 24 elements in the body, the sodium, calcium and potassium considered to be the most important elements. Ionizing radiation may lead to irregular concentration of the concentration of the […]

Abstract Benzyl alcohol is an aromatic alcohol, it’s used as asolvent for injectable preparations and classified as notorius effect excipient. It is contraindicated in infants and children less than three years of age because it causes a fatal toxic reaction. We synthesized this solvent in Therapeutic Chemistry laboratoryof pharmacy department of Sidi Bel-Abbes according the […]

Abstract In pharmaceutical industry, Boric Acid is used as an antiseptic active ingredient and it’s marketed in combination with Borax, in form of solution for ophthalmic washing with local antiseptic action and light astringent, indicated mainly in case of eye irritation. We synthesized this active pharmaceutical ingredient in Therapeutic Chemistry laboratory of pharmacy department of […]

Abstract The control of the pharmaceutical raw material is essential before the formulation to ensure the safety of the drug treatment. This study describes an application of Physico-Chemical Control of Amoxicillin Sodium quality according to the requirements of the European Pharmacopoeia 8th edition. The Amoxicillin Sodium raw material appears as substantially white powder, very hygroscopic, […]

Abstract The leaves and peels (epicarp) of Musa sapientum var. velutina are generally considered agricultural waste after the fruits have been harvested. Little or no significance is there by attached to their medicinal relevance and nutritional values. This study was carried out to determine the proximate, mineral and phytochemical constituents of banana (M. sapientum) leaves […]

Abstract Within the framework of diligent and continuous research for alternative tools and botanical products to control Spodoptera littoralis (Boisduval) (Lepidoptera: Noctuidae). Salvia officinalis (L.) (Lamiales: Lamiaceae) essential oil was assayed as an ovicidal and larvicidal. Chemical analysis of S. officinalis oil using GC-MS analysis showed monoterpenoids 1.8-Cineole (61.80%) and Camphor (17.18%) followed by monoterpenes […]

Abstract A novel potentiometric thiocyanate poly (vinyl chloride) membrane sensor with a newly synthesized Bisoprolol as an electroactive ion exchanger is developed. It offers attractive direct fast monitoring tool for SCN– in the presence of many common ions. Under the manual operation, the proposed sensor displays high selectivity, wide dynamic response range down to 1.0×10-6M […]

Abstract Salvadore persica is an evergreen shrub in the family Salvadoraceae. Among global Muslim community, Salvadore persica is commonly used for oral health hygiene. Some biologically active molecules like alkaloids, flavonoids, tannins have been isolated and identified from this plant. Phytochemical screeningof Salvadore persica roots revealed the presence of flavonoids, saponins, coumarins, alkaloids, tannins, sterols […]