The efficiency of Nigella sativa against gamma radiation on ionized serum Ca+2, K+ and Na+ levels in rats

Abstract An acquaintance of the deliberation of sodium, potassium, and calcium in the blood is essential in association with a variety of problems. There are about 24 elements in the body, the sodium, calcium and potassium considered to be the most important elements. Ionizing radiation may lead to irregular concentration of the concentration of the above-mentioned ions may effect cardiac arrhythmias, muscle contraction disorders, conflicts of neuronal activity. This study had been planned to evaluate the hazards of ionizing gamma radiation on rats. Also to test the efficiency of Nigella sativa methonelic extract as a radio-protector. Methonelic extract were orally administrated for two weeks before injection of radiation. Serum levels were investigated. The obtained results showed that ionizing radiation disturb the levels of sodium, calcium and potassium concentration. Meanwhile administration of the Nigella sativa methonelic extract effects the concentration of these ions. The Nigella sativa methonelic extract created a modulation against oxidative stress made by ionizing gamma radiation.

Keywords serum, blood, potassium, calcium, sodium, gamma radiation, Nigella sativa.

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Updated: January 20, 2024 — 8:05 am