Abstract Dexamethasone sodium phosphate and prednisolone acetate are corticosteroids, both the drugs are available in a veterinary injectable suspension dosage form as DMSP 3.291 mg per ml and PA 7.923 mg per ml. The chromatographic separation was carried out on a reversed-phase C18 column (250mm X 4.6 mm, 5µm) in isocratic mode using acetonitrile: phosphate […]

Abstract Cola parchycarpa (monkey cola) has been one of the underutilized Tropical plant in Tropical African sub regions. It is among some of the valuable fruit species whose potentials have not been fully realized. In recent times, work has been carried out on the proximate and phytochemical properties of the cola but no result on […]

Abstract Acetylsalicylic Acid (ASA) is the first active pharmaceutical ingredient (API) obtained by synthetic drug chemistry ‘ Therapeutic Chemistry’. ASA is one of the most commonly used analgesic and antipyretic medication worldwide, having been in clinical use for over 100 years. We synthesized this active pharmaceutical ingredient in Therapeutic Chemistry laboratoryof pharmacy department of Sidi […]

Abstract Worldwide, traditional medicine is still playing a vital role in primary health care and numerous pharmacological reports on the impact of bioactive phytochemicals on human physiology even potentiated the applications of medicinal plants.In this study, Acacia nilotica Subsp. nilotica oil has been analyzed by GC-MS. The analysis showed 26 components. Major constituents are : […]

Abstract Corchorus olitorius L. is a vegetable in the family Tiliaceae. It is widely grown in northern and central Sudan both under irrigation and rain-fed conditions. Seeds, leaves, roots and stems are used in traditional medicine. Leaves are used as demulcent, tonic and laxative. Leaves are also used against cystitis, dysuria and gonorrhea. Seeds are […]

Abstract Asparagus racemosus is commonly known as Shatavari having a place in the family Asparagaceae that is extensively present in tropical and subtropics of Asia, Australia, and Africa. Traditionally it was used as galactagogue, aphrodisiac, Rasayana, antiepileptic, adaptogenic, general health tonic and in numerous female reproductive system problems. Now a day’s extensive research has been […]

Abstract Annona senegalensis Persoon is a small tree or herb in the family Annonaceae. All parts of the plant find some applications in ethnomedicine. Leaves are used by traditional healers against tuberculosis, small pox and yellow fever. Root is used against snake bite, gastritis, sexual impotency, infectious diseases and erectile dysfunction. In this study Annona […]

Abstract Shampoo is the most commonly used hair care product, typically in the form of viscous liquid. Shampoos are primarily been products aimed at cleansing the hair and scalp. In the present scenario, it seems improbable that herbal shampoo, although better in performance and safer than the synthetic ones, will be popular with the consumers. […]

Abstract Acetylcholinesterase (AChE) is essentially a feasible target for the symptomatic improvement in Alzheimer’s disease (AD).  Meanwhile, Alzheimer’s (AD) is a neurodegenerative disease which accounts for an estimated 60%–80% of dementia cases.  This study investigates bioactive constituents Piper betel L as possible Acetylcholinesterase (AChE) inhibitor using pharmacophore modelling and molecular docking approach. The docking score […]

Abstract In this paper, we demonstrate how pharmacophore modelling was used to design the analogues of 2-chlorobenzimidazole and the application of molecular docking studies in the evaluation of the ligand affinity for the target.  The lead molecule (1-benzyl-2-chloro-1H-benzimidazole) had the highest docking score of -8.0 kcal/mol and was observed to interact with 17 amino acids […]