Abstract Annona senegalensis Persoon is a small tree or herb in the family Annonaceae. All parts of the plant find some applications in ethnomedicine. Leaves are used by traditional healers against tuberculosis, small pox and yellow fever. Root is used against snake bite, gastritis, sexual impotency, infectious diseases and erectile dysfunction. In this study Annona senegalensis oil was studied by GC-MS. The oil was also evaluated for antimicrobial activity. The GC-MS analysis showed 22 components dominated by: 9,12-octadecadienoic acid methyl ester (38.36%), 9-octadecenoic acid methyl ester (21.57%), hexadecanoic acid methyl ester (18.12%) and methyl stearate (14.47%). The oil showed good activity against Pseudomonas aeruginosa and moderate activity against Escherichia coli and Candida albicans.
Keywords Annona senegalensis, Oil, GC-MS Analysis, Antimicrobial Activity.