Formation and phase transition enthalpies for captopril

Abstract Combining solution calorimetry data with quantum chemical thermochemistry, a series of thermochemical parameters for captopril were obtained, as follows:  Δ_solH^θ (in water) = 12.26 ± 0.4kJmol^-1; Δ_solvH^θ= -53.43kJmol^-1;Δ_cr^gH^θ = 65.70 kJmol^-1, Δ_cr^lH^θ= 19.53kJmol^-1;Δ_l^gH^θ= 46.17 kJmol^-1;Δ_f^gH^θ= -623.10 kJmol^-1, Δ_f^lH^θ = -576.93 kJmol^-1;   Δ_f^crH^θ= -557.40  kJmol^-1; C_v= 231.72 JK^-1mol^-1andC_p= 240.03 JK^-1mol^-1.

Keywords Captopril; Solution Calorimetry; Thermochemistry; Formation enthalpies.

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