Abstract In this study, bentonite based catalyst was prepared by impregnation methods in potassium hydroxide solution (35 wt.%). The catalysts were calcined at 500 for 3 h. The best reaction conditions in the presence of KOH/bentonite were determined while modifying the catalyst to soybean oil ratio and the reaction time. Bentonite was proved to enhance […]
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Investigation of Antioxidant, Biological and Acidic Properties of New 3-Alkyl(Aryl)-4-(3-acetoxy-4-methoxybenzylidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones
Abstract Some novel 3-alkyl(aryl)-4-(3-acetoxy-4-methoxybenzylidenamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (4a-h) were synthesized from the rections of 3-alkyl(aryl)-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2a-h) with 3-acetoxy-4-methoxybenzaldehyde (3). The new eight compounds were characterized using by elemental analyses and IR, 1H-NMR, 13C-NMR and UV spectral data. In addition, the synthesized compounds were analyzed for their in vitro potential antioxidant activities in three different methods. Antibacterial activity of […]
Antioxidant Status in Aluminum Intoxified Male Wistar Albino Rats
Abstract Oxidative stress is associated with increased production of oxidizing species (from reactive oxygen species or transition metals) or a significant decrease in the effectiveness of antioxidant defense. Aluminum toxicity was investigated using antioxidant status in serum of male Wistar albino rats. Antioxidants studied in this work include superoxide dismutase (SOD) and glutathione S- transferase […]
Preparation of a drug carrier through supramolecular hydrogel based on poly(ethylene glycol) methyl ether- folic acid – α-cyclodextrin for controlled delivery of Doxorubicin
Abstract This study is aimed at developing novel, inexpensive hydrogels for containing drug and with the potential for targeting cancer cells in vitro. In this work, Folic acid has been conjugated with α-Cyclodextrin and then used as a building block for constructing novel supramolecular hydrogels together with Poly(ethylene glycol) methyl ether in aqueous solutions. Resultant […]
Determination of Secondary Metabolites and Biological Potential of Gnetun africanum (Okazi) Leaves
Abstract The ethanol, methanol, n-hexane and aqueous extracts of Gnetum africanum leaves were investigated for phytochemical studies and antibacterial assay using Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, Penicillium chrysogenum and Aspergillus fumigatus. The phytochemical analysis revealed the presence of tannins, saponins, glycosides, steroids in varying amount and the absence of flavonoids and anthraquinones. The antimicrobial […]
Assessment of the Phytochemical constituents and in-vitro antibacterial activity of Vernonia amygdalina extracts on someclinical isolates
Abstract Antimicrobial resistance is on the rise and efforts are consequently being strengthened towards the search and improvement of sturdier antimicrobial agents with expectant safety and efficacy. This study was conducted to determine the phytochemical analysis and antibacterial activity of Vernonia amygdalina (bitter leaf) extracts obtained from a market in Sokoto state Nigeria on some […]
Effect of Various Starches on the Physicochemical and Sensory Characteristics of Tomato Paste
Abstract This research had been carried out to identify the effect of starches which are one of the most important value added food ingredient used in numerous food industries, on the physicochemical and sensory characteristics of tomato paste. In this study four types of starches including potato starch, rice starch, yam starch, and corn starch […]
Drug Abuse and Substance Dependence among Youths in Contemporary Society
Abstract A healthy nation is a wealthy one. One can conclude that a nation full of drug abusers is a nation set for destruction and without labour force for the economic development. Since the youths are future leaders of any nation, problem of youths should become problem of all and the welfare of the youths […]
Formation and phase transition enthalpies for captopril
Abstract Combining solution calorimetry data with quantum chemical thermochemistry, a series of thermochemical parameters for captopril were obtained, as follows: ΔsolHθ (in water) = 12.26 ± 0.4kJmol-1; ΔsolvHθ= -53.43kJmol-1;ΔcrgHθ = 65.70 kJmol-1, ΔcrlHθ= 19.53kJmol-1;ΔlgHθ= 46.17 kJmol-1;ΔfgHθ= -623.10 kJmol-1, ΔflHθ = -576.93 kJmol-1; ΔfcrHθ= -557.40 kJmol-1; Cv= 231.72 JK-1mol-1andCp= 240.03 JK-1mol-1. Keywords Captopril; Solution Calorimetry; Thermochemistry; […]
Effect of Chronic Smoking on Mouse Corpus Cavernosum and Protector Role of Alpha-linolenic Acid
Abstract Studies have shown the antioxidant and anti-inflammatory activity of alpha-linolenic acid, one of the omega 3 fatty acids found abundantly in linseed oil. Cigarette smoke causes impotence as it contains many harmful components and increases oxidative stress. Therefore, we planned to investigate whether or not alpha-linolenic acid has protective effect against impotence due to […]