Abstract The aim of this study was to isolate and evaluate the antimicrobial constituent of the leaves of Pterocarpus santalinoides DC (Fabaceae) growing in the tropical rain forest region of Nigeria, Sub Saharan Africa. The powdered leaf materials were defatted with n-hexane and extracted in a soxhlet extractor with 90.0 % methanol. The methanol extract […]

Abstract Doxorubicin (Dox) is a chemotherapy drug used for treatment of wide variety of cancers and the most effective antitumor agents, soon proved to be hampered by such serious problems as the development of cardiotoxicity and heart damage by producing free radicals and oxidative stress along the period of treatment. The current study aims at […]

Abstract Previous studies have shown that Portulica Oleraceaeethanolic extractcan significantly modulate the activity of several drug metabolizing enzymes, this may affect the bioavailability of drugs resulting in over dose or less therapeutic effects. This study was designed to assess the inhibitory effects of cisplatin (CDDP) and paclitaxel (PAX) on two types of CYP450 isoformers namely: […]

Abstract This study was aimed at investigating the haematological and histological effects of ethanolic leaves extract of Jatropha curcas on Plasmodium berghei infected mice. Forty eight mice weighing between 22-24g were assigned into six study groups of eight mice each. Forty mice were parasitized by Plasmodium berghei and used for extract and orthodox treated groups […]

Abstract This study was carried out to investigate the effect of Andrographis paniculata leaf extract of ethanol, methanol and petroleum ether on serum electrolytes, urea, and serum enzymes as indices of toxicological importance in wistar rats. Eighty (80) female wistar rats weighing between 225-230 g were used for thee study. Rats were divided into ten (10) […]

Abstract Current study aimed to maximize multiplication rate, growth parameters and producing superior plantlets which can tolerate acclimatization conditions of Conadria fig cultivar through utilizing of Thidiazuron (TDZ), isopentenyladenine (2iP) separately. Shoots- that passed establishment stage- were cultured on MS medium that contained different concentrations of TDZ and 2iP (0.5,1 and 1.5 mg/l). In addition, […]

Abstract A total of fifty seven isolates of Entercoccus faecalis (N=42) and E. faecium (N=15) from infected wounds were screened for their resistance against 17 antibiotics including vancomycin. E. faecalis isolates demonstrated absolute resistance (100%) against eight antibiotics: chloramphenicol, nalidixic acid, gentamicin, streptomycin, tetracyclin, erythromycin, penicillin G and lincomycin. While isolates of E. faecium revealed […]

Abstract Microdesmis puberula is a plant that is used in traditional medicine for the treatment of diarrhea, stomach-ache, intestinal worms, menstrual complaints, sterility, miscarriage, loss of virility and venereal diseases, treat skin conditions, renal pain, severe headache, erectile dysfunction, and snake bite. In this work, methanol and petroleum ether extracts of the stem of Microdesmis […]

Abstract Cocoa (Theobroma cacao L.), and its derived product chocolate, are foods with recognized beneficial health properties, mainly associated with their high content of polyphenols and other bioactive compounds. In Perú there are several companies engaged in the manufacture of products based on Peruvian cacao. There is for example La Ibérica, a Peruvian company located in […]

Abstract This work analyzed ten capsules of amocycillin 500 mg each from drug resolving stores (shop 1), Opaclsas Pharmacy (shop 2), Happy Home Pharmacy (shop 3), Cheff Pharmacy Ltd (shop 4) Chimezie Medicine Stores (shop 5). The anti-hypertensive drugs (Nifedipine, 20 mg) were obtained from drug resolving stores (shop 1), Happy Home Pharmacy (shop 2), […]