Abstract To evaluate comparative cytotoxic and thrombolytic activity of crude methanol extract of F. stricta and N. nouchali leaf. The screening of cytotoxic activity was done using brine shrimp lethality bioassay while the thrombolytic activity was evaluated using the in vitro clot lysis model. In a brief, venous blood drawn from five healthy volunteers was […]
Guajaphenone C and D: two novel benzophenone glycosides from Psidium guajava (Linn.) leaves
Abstract A guided fractionation and characterization of the methanol extract from the leaves of Psidium guajava L. (Myrtaceae) yielded two new benzophenone glycosides, Guajaphenone C (I) and Guajaphenone D (II) together with three known compounds, Guajaphenone A (III), Garcimangosone D (IV) and Guaijaverin (V). Their structures were elucidated by analysis of spectroscopic data including 1D […]
Fundamental Role of Oxidative Stress in the Pathophysiology of Preeclampsia: A Review
Abstract Oxidative stress and systemic inflammatory response can emerge at the same time, exacerbate the effect of the other, and cause irreversible damage. In addition to the fundamental role of oxidative stress in the pathophysiology of preeclampsia, molecular evidence of high levels of endoplasmic reticulum (ER) stress is also found. Searches were conducted by two […]
Investigation of Pharmaceutical Nanocapsules of Iron/Alginate Characters via Coacervation Technique
Abstract Microencapsulation is a process in which solid, liquid or gas components are covered with a septum. The present study has focused on the effect of stirring to produce ferric saccharate capsules with alginate coating applying the coacervation method so that we can obtain the best capsules for fortification of hydrated and dehydrated food products. […]
Wastewater Treatment in Pharmaceutical Company through Fuel Cell and Osmotic Membranes and Investigation of their Microbiological Effects
Abstract Microbial fuel cell (MFC) and nano sized membrane bioreactor (NSMBR) are both promising technologies for wastewater treatment in pharmaceutical company, but both with limitations. In this study, a novel MFC–MBR integrated system, which combines the advantages of the individual systems, was proposed for simultaneous wastewater treatment and energy recovery. A new hybrid, air-bio cathode […]
Investigation of Interleukin 2 as Signaling Molecule in Human Serum Albumin
Abstract Psoriasis, Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin. These skin patches are typically red, itchy, and scaly. Interleukin 2 treatment reduces the relapse rate in Psoriasis, but the exact mechanism of action of the drug has remained elusive. CD73 (ecto-5′-nucleotidase) is an ectoenzyme, which produces adenosine from adenosine monophosphate […]
Renal Failure: A Review
Abstract Advanced Renal Failure or ESRD is one of the most serious and growing issues in the community necessitating the delivery of appropriate services to patients suffering from the disease. Carrying out medical interventions in the early stages of chronic renal failure can delay disease progression and reduce mortality. Results of the Literature review were […]
Hypertensive Disorders in Pregnancy: A Review
Abstract Hypertension disorders are the most commonly diagnosed pregnancy complications and involve 5 to 10% of all pregnancies (1). These disorders account for, roughly, 16% of maternal mortality in developed countries. Hypertension disorders are categorized as chronic hypertension and a group of pregnancy-specific hypertension, including pregnancy and preeclampsia. Searches were conducted by two independent researchers […]
Acceleration of vegetative growth of wheat (Triticum aestivum L.) using [1,3]oxazolo[5,4-d]pyrimidine and N-sulfonyl substituted 1,3-oxazole
Abstract Wheat (Triticum aestivum L.) is an important cereal crop cultivated in the most economically developed coutries. The elaboration of new effective growth regulators for intensification of seed germination stage and vegetative growth of wheat is an actual problem for modern agriculture. In our work the comparative analysis of regulating activity of low molecular weight […]
Diffusion Influenced Non-equilibrium Gating Processes of a Voltage-gated Potassium Ion Channel
Abstract Here we have studied the kinetics as well as the energetics of a diffusion influenced nonequilibrium gating process of a voltage-gated K-channel for a oscillatory voltage through the master equation description. A diffusion-influenced five-state Hodgkin-Huxley type voltage-gated scheme is proposed on the basis of the established findings that the K-ions can diffuse through a […]