Abstract Psoriasis, Psoriasis is a long-lasting autoimmune disease characterized by patches of abnormal skin. These skin patches are typically red, itchy, and scaly. Interleukin 2 treatment reduces the relapse rate in Psoriasis, but the exact mechanism of action of the drug has remained elusive. CD73 (ecto-5′-nucleotidase) is an ectoenzyme, which produces adenosine from adenosine monophosphate (AMP) precursor by enzymatic dephosphorylation. In this study, a validated and rapid HPLC method for quantification of human serum albumin in interleukin 2 biopharmaceutical formulation was developed and linearity, robustness, specificity, accuracy and precision of samples were determined.
Keywords Psoriasis; Human Serum Albumin; Interleukin 2; robustness; specificity.