A Density Functional Theory Study on Molecular Structure and Infrared Spectrum for Antimycobacterial [Pd(C-bzn)(SCN)(dppp)] Compound

Abstract The organometallic compound [Pd (C-bzan) (SCN) (dppp)] {bzan=N-benzylideneaniline, dppp = 1,3-bis(diphenylphosphino)propane} with antimycobacterial activity was studied by the Handy’s OPTX modification of Becke’s exchange functional by using the Vosko, Wilk, and Nusair 1980 correlation functional (III) quantum chemical approach. The theoretical geometric parameters showed that the coordination geometry of the palladium atom is square […]

Synthesis, DNA Interaction and Cytotoxic Activity Studies of a Novel 2,1,3-Benzothiadiazole-Benzimidazole Derivative

Abstract Benzimidazoles and benzothiodiazoles are biologically active heterocyclic compounds. In here, a new compound 4-(1H-benzimidazol-2-yl)-7-bromo-2,1,3-benzothiodiazole containing both heterocyclic ring systems was prepared. The highest occupied molecular orbital (HOMO) and the lowest unoccupied molecular orbital (LUMO) of the new compound was calculated using the Spartan 10 program. The compound binds to DNA with a moderate strength, […]

Optimization of 3-Dichloromethyl-1,2,2-trimethylcyclopentanecarboxylic Acid Synthesis

Abstract 3-Dichloromethyl-1,2,2-trimethylcyclopentanecarboxylic acid is used in the synthesis of biologically active substances with a trimethylcyclopentane moiety. The procedure of obtaining of the aforementioned acid has been optimized using mathematical planning of the experiment. The reaction conditions and the amounts of reagents are determined. As a result, technique was simplified, and its duration was decreased. Keywords […]

Constituents and Antimicrobial Activity of Sudanese Haplophyllum tuberculatum A. Juss (Rutaceae) Oil

Abstract Phytotherapy is still playing a vital role in primary health care in developing countries and intensive literature reports on the impact of secondary metabolites on human physiology potentiated the applications of medicinal plants. Haplophyllum tuberculatum is a plant of many medicinal attributes.The plantis used traditionally against a wide range of diseases. In this study, […]

Adsorption and Corrosion Inhibitive Properties of 1-Methyl-1H-imidazole-2-thiol on Mild Steel in Acidic Environment

Abstract The inhibition effect of 1-methyl-1H-imidazole-2-thiol (MTI) on the corrosion of mild steel in 1 M HCl, 3M HCl, 0.5 M H2SO4 and 1.5 M H2SO4 solution was investigated electrochemical methods (potentiodynamic polarization curves, resistance polarization and electrochemical impedance spectroscopy). The results show that MTI is a very good inhibitor, and is more efficiency in […]

Biosorption of Ammonia from Wastewater using Eichhornia Crassipes Leaves Powder

Abstract An increasing of ammonia concentration in water is toxic to all forms of aquatic life. The adsorption behavior of a low-cost adsorbent, Eichhornia Crassipes leaves powder (ECLP), with respect to ammonia, has been conducted to consider its application for ammonia removing from drainage wastewater. The batch method was considered for ammonia removal to determine […]

Antimicrobial Activity and GC-MS analysis of Sudanese Carthamus tinctorius (Compositeae) Oil

Abstract Carthamus tinctorius is an annual highly branched herb in the family Compositeae. The palnt has been used traditionally as purgative, analgesic and antipyretic. Carthamus tinctorius is also used by traditional healers against rheumatism, bronchitis, menstrual cramps and whooping cough. In this study the oil from Carthamus tinctorius was studied by GC-MS and the antimicrobial […]

The Relationship between Periodontal Status and Pre–Eclampsia among Pregnant Ladies in Khartoum State, Sudan

Abstract Pre-eclampsia is a vascular disorder of pregnancy characterized by blood pressure and proteinuria and it is a major cause of maternal and perinatal mortality and morbidity worldwide. Several studies have suggested an association between periodontal diseases and pre-eclampsia. The aim of this study was to determine possible relationships between periodontal diseases and pre-eclampsia in […]