Synthesis and Characterization of Some Novel Potential Biologically Active 2-Ethoxy-4-{[1-(4-piperidinecarboxyamide-1-yl-methyl)-3-alkyl-4,5-dihydro-1H -1,2,4-triazol-5-on-4-yl]-azomethine}-phenylbenzenesulfonates.

Abstract In this study, because of potential biological activity, five new 2-ethoxy-4-{[1-(4-piperidinecarboxyamide-1-yl-methyl)-3-alkyl-4,5-dihydro-1H-1,2,4-triazol-5-on-4-yl]-azomethine}-phenylbenzenesulfonates (2a-e) were synthesized by the reactions of2-ethoxy-4-[(3-alkyl-4,5-dihydro-1H-1,2,4-triazol-5-on-4-yl)-azomethine]-phenylbenzenesulfonates(1a-e) with formaldehyde and 4-piperidinecarboxamide. The structures of five new compounds characterized from the mass, IR, ¹H-NMR, ¹³C-NMR spectral data.

Keywords 4,5-Dihydro-1H-1,2,4-triazol-5-one, Schiffbase, Mannih base, Synthesis.

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