Synthesis and Characterization of Some New Potential Biologically Active 3-Alkyl(Aryl)-4-(methoxysubstituebenzylideneamino)-4,5-dihidro-1H-1,2,4-triazol-5-ones

Abstract In the present study, two new 3-alkyl-4-(3-methoxybenzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (3b,c) and three new 3-alkyl-4-(3,4-dimethoxybenzylideneamino)-4,5-dihydro-1H-1,2,4-triazol-5-ones (4a-c) were synthesized by the reactions 3-methoxybenzaldehyde and 3,4-dimethoxybenzaldehyde with corresponding 3-alkyl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2a-c). The structures of five new compounds characterized from the IR, 1H NMR and 13C NMR spectral data.

Keywords 1,2,4-triazol-5-one, Schiff base, synthesis.

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Updated: January 20, 2024 — 7:39 am