Abstract A series of new phenothiazine derivatives have been synthesized in which diphenylamine on treatment with sulphur give 10H-phenothiazinewhich on reaction with ethylchloro acetate yielded 2-(10H-phenothiazin-10-yl)acetate which on further treatment with hydrazine hydrate produced 2-(10H-phenothiazin-10-yl) acetohydrazide. Condensation of chief intermediate with various benzaldehyde derivatives afforded N’-(substitutedbenzylidene)-2-(10H-phenothiazin-10-yl) acetohydrazide. All the synthesized derivatives have been characterized by FTIR, 1H NMR, Mass, UV-visible and elemental analysis.
Keywords Phenothiazine, Ethylchloroacetate, Hydrazine hydrate, p-Fluorobenzaldehyde, FTIR.