Abstract Information on plants used traditionally in Sudanese system of medicine is very scarce. Hence this study was undertaken to investigate the chemical constituents of Petroselinum crispum fixed oil and to evaluate its potential antimicrobial activity. 62 components were detected by GC-MS. Major components are: apiol (36.44%), 9-octadecenoic acid methyl ester (27.17%), 4-Methoxy-6-(2-propenyl)-1,3-benzodioxole12.12%) and 9, 12-octadecadienoic acid methyl ester (8.32%)
The antibacterial activity of the oil was evaluated via the diffusion bioassay against five standard human pathogens (Gram positive: Staphylococcus aureus and Bacillus subtilis; Gram negative: Escherichia coli and Pseudomonasa aeruginosa and the fungal species Candida albicans). The oil showed good activity against Staphylococcus aureus and Bacillus subtilis and also showed weak activity against Escherichia coli and Pseudomonas aeruginosa.