Inhibitory effect of ethyl acetate fraction of Talinum triangulare (jacq.) Willd on Fe2+ induced lipid peroxidation in albino rat tissue homogenates-in vitro

Abstract In the current study, total phenolic content (TPC) of ethyl acetate fraction of Talinum triangulare was determined using Folin-Ciocalteu method and the results indicated significant (p<0.05) difference within various concentrations examined with considerable increase as the concentration of the solvent extract increased, also, the ability of the solvent fraction of the plant to inhibit the formation of malondialdehyde (MDA) in Fe2+-induced lipid peroxidation of some selected tissue homogenates was consideredin vitrothrough TBARS and the results indicated significant (p<0.05) difference in the percentage inhibitions at moderate concentrations ranging from 0.33-3.33µg/ml. These results indicate phyto-nutritional endowment of Talinum triangulare which could be useful as aid in treating ailments and some common diseases.

Keywords Antioxidants, oxidative stress, total phenolic, TBARS.

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Updated: January 20, 2024 — 10:05 am