Abstract Oxazine compounds was found to have versatile application in pharmacology and medicine now a days .Their utility and application as drug and co-drug have drew attention of chemist to find different ways for the synthesis of this important type of heterocyclic compounds. They are important not as pharm chemical compounds but also as synthetic intermediates for other chemical and medical compounds .Accordingly we tried to find green and friendly procedure for the synthesis of new oxazine compounds( S1-6) using grinding technique .The synthesized compounds were studied by spectral methods and are discussed.
Keywords Green, Approach, Synthesis, New, Oxazines.