Abstract Leucaenia leucocephala is native to southern Mexico, northern and central America. Leucaenia leucocephala is a multipurpose tree providing food, medicine, shade and firewood. In this study Leucaenia leucocephala oil was analyzed by GC-MS. Thirty constituents were detected being dominated by: 9,12-octadecadienoic acid-z,z- methyl ester (37.29%); hexadecanoic acid methyl ester (18.17%). The oil was evaluated for antimicrobial activity against five standard microorganisms using the disc diffusion method. The studied oil showed moderate activity against Staphylococcus aureus. It also exhibited partial activity against Pseudomonas aeruginosa.
Keywords Lucaena leucocephala, Oil, GC-MS analysis, Antimicrobial Activity.