Abstract The dependence of the anticorrosion properties of benzylated N-arylnicotinamides upon corrosion of 08kp steel in 3M HCl at 80 ° C on their energy characteristics was investigated. For cations of these structures, the optimized geometries and quantum-chemical parameters of ENOMO, ELUMO, and ΔE = ELUMO-EHOMO were calculated and the dependences of the reduced corrosion […]
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GC-MS Analysis and Antimicrobial Activity of Sudanese Acacia polyacantha Willd. (Fabaceae) Seed Oil
Abstract The present study was carried out to characterize the constituents of Acacia polycantha seed oil and to assess its antimicrobial activity. Thirty two components were detected by GC-MS analysis being dominated by: 9,12-octadecadienoic acid methyl ester (27.95%), methyl stearate (17.13%), hexadecanoic acid methyl ester (13.30%), 9-octadecanoic acid(Z) methyl ester (9.57%). The antimicrobial activity of […]
Chemical Constituents and Antimicrobial Activity of Sudanese Lucaena leucocephala (Fabaceae) Oil
Abstract Leucaenia leucocephala is native to southern Mexico, northern and central America. Leucaenia leucocephala is a multipurpose tree providing food, medicine, shade and firewood. In this study Leucaenia leucocephala oil was analyzed by GC-MS. Thirty constituents were detected being dominated by: 9,12-octadecadienoic acid-z,z- methyl ester (37.29%); hexadecanoic acid methyl ester (18.17%). The oil was evaluated […]
Palladium Catalyzed Anilino Analogues of Angular Penta-Cyclic Phenothiazines: Novel Human Cholinesterases Inhibitors
Abstract The synthesis of novel 8-chloro12H- 5,14- di hydro- quinoxalino [2,3, a] – penta cyclic phenothiazine (16) and its anilino derivatives (18 a-h) are reported. The preparation followed the water-mediated catalyst pre-activation method as reported by Buchwald and co-workers. Structures were established by analytical and spectral data. The compounds (18 a-h) were evaluated for inhibitory […]
Paraquat-induced Oxidative Injury in Erythrocytes is correlated with Decreased Magnesium Level and Reduced Antioxidant Activity
Abstract Paraquat (PQ) is commonly used in controlling wild plants in agriculture and public environment. PQ ingestion in human mainly dies for hypoxia due to the enhanced oxidative stress. Magnesium and antioxidants play important role in erythrocytes. This study attempted to investigate whether PQ-induced oxidative injury in erythrocytes is involved in the alterations of antioxidants […]
Constituents of Sudanese Cassia auriculata Linn.(Caesalpiniaceae) Oil
Abstract Traditional medicine is playing an important role in primary health care in developing countries. Increasing research on the impact of secondary metabolites on human physiology potentiated the applications of medicinal plants. Cassia auriculata L. is a plant of many medicinal attributes. The plant is used against diarrhea, leprosy, intestinal worms, female infertility, rheumatism and […]
Constituents and Antimicrobial Activity of Sudanese Lycopersicum esculentum (Solanaceae) Oil
Abstract Lycopersicum esculentum is worldwide cultivated for its nutritional value. Fruits of Lycopersicum esculentum is rich in lycopene which is a carotenoid with beneficial health effects. This plant is rich in vitamins and contains many minerals including iron, calcium and phosphorus. Fruit juice is used traditionally against wound bleading, scorpion bite and edema. In this […]
In utero exposure to bisphenol A alters prostatic responses in adult male rats: Protective effects of melatonin
Abstract Exposure to bisphenol A (BPA), an endocrine disrupting chemical (EDC), has been shown to result in a number of reproductive dysfunction. Melatonin (MLT) is a potent antioxidant known to protect against EDC-induced toxicity. We aimed at investigating the protective effects of MLT on prostate gland dysfunction in the F1 adult male Wistar rats exposed […]
Comparative Study of the Antibacterial and Antioxidant Properties of Raw and Tannic Extract of the Bark of Musanga cecropioides R.Br. & Tedlie (Urticaceae)
Abstract The general objective of this study was to evaluate a comparative study of the antimicrobial and antioxidant activities of the crude and tannic bark extracts of Musanga cecropioides. The plant material was extracted by maceration using three solvents namely, ethanol, hydro-ethanolic and aqueous solvents. The phytochemical profile of the plant extracts was determined to […]
Process Validation of Solid Dosage Form
Abstract Process validation is an essential part for the safety of drug products and also to maintain the quality of the products. It is a fundamental component for assuring the quality system used by pharmaceutical industries. Process validation is the key element to ensure the identity, purity, safety, and efficacy of drug products. The process […]