Abstract Chalcone is an aromatic ketone that forms a central core for a variety of important biological compounds, which are collectively known as chalcones. They consist of open-chain flavonoids in which the two aromatic rings are joined by a three-carbon α, β-unsaturated carbonyl system. They are of a large distribution amongst plant Kingdom. This review aims to highlight the geographical distribution of Dorstenia species in Cameroon and the specificity of Chalcones isolated in those plants species. The hemi-synthetic derivatives as well as the biological activities of some isolated compounds are also mentioned. This review is expected to be a comprehensive, authoritative, and critical review of the chalcone template to the chemistry community.
Keywords Moraceae, Dorstenia, Chalcones, biological activities.