Anthelmintic and Antioxidant Activity Study of Aerial Parts of Hedyotis Corymbosa

Abstract This study was conducted to investigate phytochemical constituents, anthelmintic and antioxidant activity of aerial parts of Hedyotis corymbosa. Phytochemical constituents were determined by qualitative chemical tests and carbohydrate, glycoside and flavonoid were found in the methanolic and ether extracts of the aerial parts. In vitro anthelmintic activity was carried out against Pheretima posthuma. The parameters like: time of paralysis and time of death were determined by using the extract at the concentrations of 10, 25 and 50 mg/ml. The extract exhibited significant anthelmintic activity at highest concentration of 50 mg/ml as compared with piperazine citrate (10 mg/ml) as standard reference and distilled water as control. For antioxidant properties- total phenols, total flavonoids, total antioxidants, DPPH free radical scavenging capacity, cupric reducing antioxidant capacity (CUPRAC) and reducing power of the extracts of the sample were assessed. From the antioxidant study it was found that the plant has poor antioxidant activity.

Keywords Hedyotis corymbosa, Methanolic and Ether Extract, Anthelmintic, Antioxidant Activity.

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Updated: January 20, 2024 — 8:21 am