Abstract The preferred route of drug administration is via the oral route. Gastroretentive Drug Delivery Systems (GRDDSs) represent an innovative strategy within the pharmaceutical sector. Gastroretentive drug delivery systems (GRDDs) refer to dosage forms that are designed to remain in the stomach for an extended period of time. Gastroretentive drug delivery systems (GRDDSs) have the potential to improve the controlled release of drugs that have a specific absorption window by gradually administering the drug over an extended period until it reaches the intended site of absorption. The use of GRDDS is advantageous for drugs due to their ability to enhance bioavailability, therapeutic efficacy, and potential for dose reduction. Additionally, GRDDS can improve drug solubility, particularly for drugs that exhibit low solubility in high pH environments. This paper presents a discussion on the Gastroretentive Drug Delivery System of antihypertensive medication.
Keywords Gastroretentive Drug Delivery System, Floating, Antihypertensive, GRDDS, FDDS.