Abstract This review highlights various methods for the synthesis of glycoconjugates and recent progress in the development of glycosylated derivative therapeutics. Review lies in the discussion of recent mechanistic theories and supporting experimental evidences on chemical glycosylation on compounds. The impact of glycosylation is noteworthy in overcoming the existing barriers that restrict oral and brain delivery of drugs.
Keywords Glycosylation, Glycoconjugates, Antibacterial activity, Antiviral activity, Antimalarial activity, Antitumor activity.