Abstract The current study was undertaken to assess the complementary action of pepper as bioenhancer in the treatment of cancer along with mercaptopurine. Haemoglobin content and RBC count were significantly decreased and total WBC count was significantly increased in the tumour group as compared to the normal group. Treatment with both Mercaptopurine (5mg/kg) and Piper nigrum (200mg/kg) alone restored the altered parameters towards the normal values but combination therapy of Mercaptopurine along with Piper nigrum showed statistically very significant effects.
Keywords cancer, bioenhancer, pepper, tumour, Haemoglobin, Lipid peroxidation.