Abstract Salvia officinalis is distributed in southern Asia, central and south America and around the Mediterranean region [3]. The plant has been used traditionally for centuries against sore throat, liver disorders, indigestion and gastroenteritis. Salvia officinalis is also used to improve regularity of menstrual cycle and to improve memory. In this study Salvia officinalis essential oil was analyzed by GC-MS which revealed 42 constituents. The major constituents of the oil are: eucalyptol (30.36%) and 2-bornanone (13.02%) at a concentration of 100mg/ml the oil showed significant activity against Pseudomonas aeruginosa, Bacillus subtilis, Staphylococcus aureus and the fungal species Candida albicans. It also exhibited significant activity against Pseudomonas aeruginosa at a concentration of 50mg/ml. Except for Staphylococcus aureus the oil showed a dose-dependent antimicrobial activity. In the DPPH assay, Salvia officinals oil showed weak free radical scavenging capacity.
Keywords Salvia officinalis, Oil, Constituents, Antimicrobial Activity, Antioxidant activity.