Synthesis and Characterization of Phenothiazine Derivatives

Abstract A series of new phenothiazine derivatives have been synthesized in which diphenylamine on treatment with sulphur give 10H-phenothiazinewhich on reaction with ethylchloro acetate yielded 2-(10H-phenothiazin-10-yl)acetate which on further treatment with hydrazine hydrate produced 2-(10H-phenothiazin-10-yl) acetohydrazide. Condensation of chief intermediate with various benzaldehyde derivatives afforded N’-(substitutedbenzylidene)-2-(10H-phenothiazin-10-yl) acetohydrazide. All the synthesized derivatives have been characterized by FTIR, 1H NMR, Mass, UV-visible and elemental analysis.

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Updated: April 26, 2017 — 5:08 pm
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