Abstract Sorafenib tosylate (SFNt) is an important numerouskinase inhibitor for the curement of cancers. It is commercially available (Nexavar) in the form of SFNt due to its poor aqueous solubility. Studies have been done to further enhance the dissolution property of the form SFNt, which could ultimately reasonable the currently high daily dose and frequency. […]

Abstract The effect of temperature on the equilibrium adsorption of Malachite green dye from aqueous solution using rectorite was studied. The equilibrium adsorption data were analyzed using three widely applied isotherms; Langmuir, Freundlich, and Redlich-Peterson isotherm. A nonlinear method was used for comparing the best fitting of the isotherms. Best fits were found to be […]

Abstract This study shows the in vitro anti-inflammatory effect of leaf extracts of Polyalthia longifolia. These were analyzed in different assays to determine their anti-inflammatory effects. Protein denaturation and RBC membrane stabilization were assayed. The results were reported as % inhibition in triplicate determination and were subjected to statistical also diclofenac sodium and Aspirin were […]

Abstract For decades, plants have been a source of inspiration for new drugs. Almost all ancient civilisations and cultures depended entirely or partially on phytotherapy because of its effectiveness, accessibility, availability and dose-related low toxicity. Thus, the know-how of traditional healers is a starting point for phytochemical and pharmacological investigation of these natural medicines. Therefore, […]

Abstract Shea butter seeds were collected and processed. 500.000 g of the processed seeds were subjected to soxhlet extraction for 5 hours at 85oC using n-hexane (as extracting solvent). The extract (seed oil) was recovered from the extracting solvent by rotary evaporation and concentrated to a constant weight at 37 oC. A solution mixture of […]

Abstract Methylsulfonylmethane (MSM) is an organic sulfur-containing natural compound without any toxicity. MSM may have anti-inflammatory and free radical scavenging activity. The present work was done to investigate the possible protective effects of methylsulfonylmethane on acetic acid-induced colitis in rats. Colitis was induced by intracolonic injection of 5% acetic acid. Several parameters including macroscopic score, […]

Abstract Fresh waterhyacinth was collected and processed. The physical and chemical parameters of the sample (waterhyacinth) were determined. A slurry of 40.000g waterhyacinth in 1dm3 distilled water was prepared and subjected to naerobic fungal degradation at 33oC for eleven (11) consecutive days, where fermented supernatant liquid was formed. The bioliquid content of the supernatant liquid […]

Abstract This work was carried out at Jigawa Research Institute Biotechnology Laboratory Kazaure to determine callus induction potentials of 30 wheat genotypes using matured embryo as ex-plant source under different 2,4-Dichlorophenoxyacetic Acid (2,4-D) levels. The experiment had six treatments (control, 1mgl1 2,4-D, 2mgl1 2,4-D, 3mgl1 2,4-D, 4mgl1 2,4-D, and 5mgl1 2,4-D,) including control with each […]

Abstract This study determined the comparative impact of Moringa oleifera and Carica papaya leaves powder on some life stages of clarias gariepinus. 2,400 fry of Clarias gariepinus fish from the same stock were randomly stocked at 200 fish per plastic aquaria at 3 treatment levels designated control (0.00), 0.10g/l, 0.20g/l , 0.30g/l each with 4 […]

Abstract This work is on optimization and impedance study of inhibition efficiency of moringa leaf extract as corrosion inhibitor of aluminum in alkaline solution. Gravimetric method, polarization study and impedance measurement was employed in the corrosion inhibition study. Response surface methodology (RSM) was applied in the optimization process. Central composite design tool of design expert […]