Development and Evalution of Ethylcellulose Based Floating Microspheres of Atrovastatin by Novel Solvent Evaporation Matrix Erosion Method

Abstract Floating drug delivery system is one of the novel drug delivery system. Floating drug delivery system has a bulk density less than gastric fluids and thus it remains buoyant in the stomach without affecting gastric emptying rate for a prolonged period of time. Atrovastatin is a competitive inhibitor of HMG-CoA reductase with half-life 14hr. […]

Photochromic behavior of hexacyanoferrate (ii) in o-cresolphthalein system

Abstract The photo chromic behavior of Hexacyanoferrate in phthalein system was observed spectrophotometrically. Hexacyanoferrate (II) ejects electrons, which abstracts H+ from indicator molecule and this molecule of the indicator changes into their quinonoid form which is coloured.  Keywords Photochromism, o-cresolphthalein, Phthalein. Google Scholar Citation [Full Text: PDF]

New phosphoglycerides from the seeds of Lactuca sativa L.

Abstract The seeds of Lactuca sativa L. (Asteraceae) are regarded as an anodyne, galactagogue, demulcent, emollient and used to treat bronchitis, asthma and whooping cough. Phytochemical investigation of the methanolic extract of the seeds of L. sativa led to isolation of phytoconstituents characterized as glyceryl-1,2-dioleiyl-3-phosphate (1), glyceryl-1-octadec-9ʹ-enoate-3-phosphate  (2), glyceryl-1-octadec-9ʹ-enoate-2-hexadecanoate-3-phosphate (3), glyceryl-1-octadec-9ʹ-enoate-2-octadecanoate-3-phosphate (4) and β-sitosterol (5). […]

Spectral Properties and Applications of Ln (III) Ion and Their Complexes

Abstract In lanthanides transitions involve only a redistribution of electrons within the 4f-orbitals (f↔f transition) are orbitally forbidden by the selection rule. Crystal field effects in lanthanides are virtually insignificant due to 4f-electrons are well shielded from external charge by 5s2 and 5p6 sub-shells.  Their (f↔f transition) absorption bands are very sharp. Their optical spectra […]

Isoprenyl Flavone from Sida Rhombifolia

Abstract A new isoprenyl flavone has been isolated from the ethyl acetate fraction of the leaves of the Sida rhombifolia. The structure of the new compound has been established as 5, 7, 3′, 4′,-tetra hydroxy-3-isoprenyl flavone based on the spectral (UV, IR, 1H, 13C-NMR and Mass) data. Keywords Isoprenyl Flavone, Sida Rhombifolia, Isolation Google Scholar […]

Use of 5-Nitroimidazole drugs in the treatment of periodontitis

Abstract Periodontal disease, a common cause of tooth loss, is an inflammatory response to the overgrowth of anaerobic and micro-aerophilic organisms in the subgingival plaque. Various 5-Nitroimidazole chemotherapeutic agents have been discussed in this review article with a special emphasis on periodontal gels because of their relatively fast rate of drug release, ease of preparation, […]

Treatment of hypertension with Hibiscus sabdariffa in Diabetes type-II patients

Abstract The efficacy and potency of Hibiscus sabdariffa (HS) in the treatment of risk factors associated with various cardiac and hypertensive disease is presented in this paper. Anthocyanins found in abundance in Hibiscus sabdariffa sepals are generally considered the phytochemicals responsible for the antihypertensive and hypocholesterolemic effects. Decoctions and infusions of sepals and tender leaves […]

Formulation, Development and Characterization of Emulgel of a Nsaid’s

Abstract The objective of the current research work was to explore the potential of emulgel in enhancing the topical delivery of piroxicam. Emulgel formulations of piroxicam were prepared using three types of gelling agents: Carbopol 934, Xanthan gum and HPMCK15M. Based on solubility studies Tween-80 and Span-80 as emulsifiers and propylene glycol as co-surfactant were […]

Formulation and evaluation of bupropion hydrochloride sustained release tablets using combination of hydrophilic polymers

Abstract The objective of the present study was to develop the oral sustained release tablets of Bupropion hydrochloride using combination of hydrophilic polymers. Bupropion Hydrochloride is a Anti-Depressant agent used in symptomatic treatment of depression, maniac, and smoking withdrawal conditions. FT-IR studies were carried to know the interaction, showed that absence of any interactions between […]