Significance of Soluble fms-like tyrosine kinase-1 (sFlt-1), Placental growth factor (PlGF) and ratio of sFlt-1:PlGF  in Preeclampsia (PE)

Abstract: PE is heterogeneous type of disease, profoundly defined by existence of hypertension and proteinuria, mostly after 20 weeks of gestations. It was reported that placental dysfunction due to PE manifests into alteration of circulating pro-angiogenic or anti-angiogenic mediators, such as placental growth factor (PlGF), and the soluble fms-like tyrosine kinase receptor-1 (sFlt-1). We assessed […]

Knowledge, Attitude and Ethical Sensitivity of Students of Nursing and Midwifery about Medication Application

Abstract Nursing and midwifery professions require ethically sensitive approaches because they involve various applications on human beings, including medication applications. However, it is important to undertake initiatives based on scientific evidence within the framework of rules and specific procedures. To review the situation of medication applications during the training of nurses and midwives. This was […]

Potentiometric Titrations of New 1,3,5-Tri-{4-[(3-alkyl/aryl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)-azomethin]-phenoxycarbonyl} Benzenes

Abstract A series of new 1,3,5-tri-{4-[(3-alkyl/aryl-4,5-dihydro-1H-1,2,4-triazol-5-one-4-yl)-azomethin]-phenoxycarbonyl} benzenes (4) were obtained from the reactions of 3-alkyl/aryl-4-amino-4,5-dihydro-1H-1,2,4-triazol-5-ones (2) with 1,3,5-tri-(4-formylphenoxycarbonyl)-benzene (1) and characterized by IR, 1H-NMR and 13C-NMR spectral data. In addition, to investigate the effects of solvents and molecular structure upon acidity, the new nine compounds 4 were titrated potentiometrically with tetrabutylammonium hydroxide in four non-aqueous […]

The Fundamental Role of Chromatography in the Large Scale Manufacture of Plasma-Derived Medicinal Products

Abstract Plasma-derived medicinal products (PDMPs) are valuable group of medications which are used for prevention, control and treatment of several life-threatening diseases. Today, due to the increasing demand for PDMPs, the industrial scale production of these medicinal products has modified from those mainly based on cold ethanol fractionation, to combined consecutive processes including cryoprecipitation, ethanol […]

Comparative Studies on Nutritional Evaluation of Wild yam (Discorea villosa) and Other Varieties for Human Consumption

Abstract The wild yam, Discorea Villosa, alata and bulbifera tubers used for this study, was obtained from the farm in Rufus Giwa Polytechnic, Owo, Ondo State. The samples were prepared by cleaning, washing, peeling and cutting into smaller sizes, dried for one month. The sample were powdered in Willey milled at 60 mesh size and […]

Proximate and Physicochemical Properties of Flour and Oil Extracted from Raw and Boil Locust Bean (Parkia biglobosa)

Abstract Proximate composition of flour from raw and Boil (defatted) samples of locust bean as well as its physicochemical composition of the oil extracted from the two samples were determined to know their potentials for industrial and human consumption without due fermentation method normally adopted for its consumption. The results revealed that the moisture content […]

Comparative Study of the Influence of the Micellar and Ethanol Medium on the Antiradical Activity of the Aqueous Extracts of three Chewing Stick used in Benin for Oral Hygiene

Abstract Free radicals are risk factors that can lead to certain oral infections. The contributions of antioxidants is necessary to fight effectively against these free radicals, in the oral cavity. Plants being recognized as a source of natural antioxidants, chewing stick still used today in several developing countries can serve as a remedy to fight […]

Microbial Urate Oxidase as Anti Hyperuricemic Agent: Current Scenario and Future Prospects

Abstract Urate oxidase catalyzes the degradation of uric acid, a product of purine disintegration pathway, into allantoin, carbondioxide and hydrogen peroxide. Owing to its efficacious uricolytic activity, urate oxidase employed to treat hyperuricemia and gout. Urate oxidase enzyme has been isolated from a wide range of organisms, including plants, animals and microorganisms. This review catalogues […]

Expectations of Healthcare Providers in MENA region towards the Roles and Responsibilities of Clinical Research Coordinators (CRC)

Abstract Background: The role of CRC is crucial for the success of clinical trials. However, a lot of health care providers are not fully aware of the roles and responsibilities of CRC. Purpose: To explore the awareness of health care providers in MENA region about roles and responsibilities of CRC. Method: A qualitative study was […]