Abstract Z)-N-tert-butyl-1-(5-((((E)-3-(3,4-dihydroxyphenyl)acryloyl)oxy)methyl)-3,6-dimethylpyrazin-2-yl) methani mine oxide (CT-011), a novel derivative of tetramethylpyrazine (TMP) was designed and synthesized in our laboratory, can effectively scavenge free radicals and protect nerve cells. A developed and validated high performance liquid chromatography (HPLC) was used to evaluate the pharmacokinetics of CT-011, the limit of quantitywas0.02 μg/mL. Within the intravenous dose of […]

Abstract In this study, ten substituted N – ([1,3-dioxoindolin-2-yl] phenyl] sulfonyl) structures (compound 1-10), which seven of them were original synthesized using conventional and microwave synthesis methods.  In the first method the cis-1,2-cyclohexanecarboxylic anhydride and sulfa derivatives reacted under  reflux for 2-3 hours in acetic acid. In the second method the cis-1,2-cyclohexanecarboxylic anhydride and sulfa […]

Abstract This study was conducted to investigate phytochemical constituents, anthelmintic and antioxidant activity of aerial parts of Hedyotis corymbosa. Phytochemical constituents were determined by qualitative chemical tests and carbohydrate, glycoside and flavonoid were found in the methanolic and ether extracts of the aerial parts. In vitro anthelmintic activity was carried out against Pheretima posthuma. The […]

Abstract Cellular and humoral immunity on antigene Hyal is studied at mice-hybrids. Hyal possessed low immunogenic properties.Use DS,PO as immunoadjuvant towards Hyal raised it immunogenic the activity expressed in strengthening humoral of the immune response on Hyal at mice.DS also was capable to activate specific cellular reactions DTH on Hyal. Keywords Cellular humoral immunity, activity, […]

Abstract The oxidation process is essential for living organisms for energy production. However, it has been shown that free radicals generated in large quantities can activate proangiogenic factors and be involved in many human diseases such as cancers. Thus, in this work, the antioxidant activities of water, water-ethanol and ethanol extracts of three fungi of […]

Abstract Newbouldia leavis (NL) andPepper fruit(PF) leaf extracts were investigated for their ability to impede corrosion of zinc in 0.5 M HCl by gravimetric and thermometric techniques. The results obtained showed that different concentrations of the (NL and PF) extracts hinder the corrosion of zinc in 0.5 M HCl. Inhibition efficiency of each extract varies with concentration, […]

Abstract Many Acacia species find wide applications in traditional medicine. Data on the medicinally important Acacia mellifera is very scarce. This study was designed to investigate the constituents of Acacia mellifera hexane fraction and to screen its antimicrobial potential. The hexane fraction was investigated by GC-MS analysis. The gas chromatogram revealed the following order of […]

Abstract The article reveals the importance of Ibn Sina’s medical heritage. The main aspects of the revival of methods of Oriental medicine are analyzed Keywords Oriental medicine, disease, diet, therapeutic massage, food. Google Scholar Citation [Full Text: PDF]

Abstract Fennel is widely cultivated in many countries where it is used as flavouring agent. Fennel is rich in some minerals like calcium, sodium, iron, potassium and phosphorus. The plant also contains fibre (18.5%), protein (9.5 %); fats (10%) beside niacin, riboflavin and thiamine. Fennel hexane fraction was analyzed by GC-MS. Gas chromatogram revealed presence […]

Abstract The article reveals the influence of biological, social and hygienic factors on the formation of visual pathology in children. Keywords Factor, vision, training, myopia, load. Google Scholar Citation [Full Text: PDF]