Abstract Phosphorylated polysaccharides, as a very important polysaccharide, exist widely in animals, plants and microorganisms. It has a variety of biological activities such as antioxidant, immune, anti-tumor and anti-viral. According to the research, its therapeutic effect is significant, but it is not easy to extract natural phosphorylated polysaccharides, so the artificial synthesis of phosphorylated polysaccharides has become a research hotspot. The reagents used in the phosphorylation of polysaccharides and the biological activities of phosphorylated polysaccharides were reviewed in this paper.
Keywords Polysaccharide, Phosphorylated polysaccharide, Phosphorylation reagent, Biological activity.