Abstract Hyphaene thebaica L. is a type of palm tree in the family Arecaceae. In Sudan, the plant grows along Nile river banks. Hyphaene thebaica fruit oil was studied by GC-MS. The oil was also evaluated for antimicrobial activity. The GC-MS analysis showed 50 components. Major constituents are: Z,Z-9,12-octadecadienoic acid methyl ester (30.62%), hexadecanoic acid methyl ester (23.19%), 9-octadecenoic acid methyl ester (16.12%), methyl stearate (5.84%). The studied oil showed significant activity against Pseudomonas aeruginosa and Staphylococcus aureus. It also exhibited significant anticandidal activity.
Keywords Hyphaene thebaica, Oil, GC-MS analysis, Antimicrobial Activity.