Abstract Interaction of Cu complex (Salen= N, N´-ethylene bis (salicylideneimine)) with Bovine Serum Albumin (BSA) was studied by absorption spectroscopy, competitive binding study and thermal denaturation study. The protein binding affinity of Cu complex was found to be (3.0×104M−1). The binding plot obtained from the absorption titration data gives a binding constant of 3.5 (± […]

Abstract In order to ensure the optimum therapeutic effect of drug it is necessary to prepare the proper dosage form.  Solubility is a significant physicochemical factor affecting absorption of drug and its therapeutic effectiveness. Poorly water soluble compounds have both solubility and dissolution related problems which can dramatically affect their bioavailability resulting in reduction of […]

Abstract Forest fires cause loss of lives besides financial damages affecting approximately 350 million hectares of area every year in the World. YARDOP (Forest Fire Resistant) forests were developed in order to prevent these fire damages. In this study, testing areas from the fire resistant plants in the region of Kepsut/Balıkesir (Turkey) to reduce forest […]

Abstract Schiff bases are the compounds which are mainly formed by the condensation of the aldehydes and amines. Benzothiazole is a privileged heterocyclic scaffold having a benzene ring fused with a five membered thiazole ring. A few Substituted 1, 3-benzothiazole derivatives are an important class of heterocyclic compounds. In recent years heterocyclic compounds analogues and […]

Abstract The purpose of writing this review on pharmaceutical gel was to compile the recent literature with special focus on rational approach to topical formulation and basic components of topical drug delivery systems. Topical application of drugs offers potential advantages of delivering the drug directly to the site of action and acting for an extended […]

Abstract Persea americana commonly known as avocado is classified in the flowering plant family ‘Lauraceae’. It is a medicinal plant that serves as both a preventive measure and a cure to several diseases. Ethanol seed extract of Persea americana was studied for in-vitro antioxidant activity and diuretic effect. Different models such as DPPH radical scavenging […]

Abstract This study evaluated the inhibitory effects of kolaviron, a biflavonoid from Garcinia kola seed, on benzoyl peroxide (BPO)-induced free radical generation in rat’s skin. Adult male rats were administered with Group I: 0.2 ml acetone per animal as control, Group II: 100 mg of kolaviron/kg b.wt./0.2 ml acetone, Group IlI: 20 mg BPO/0.2 ml […]

Abstract Pecan [Carya illinoensis (Wangenh.) C. Koch] faces serious problem of alternate bearing producing large number of fruits of low quality in one year, followed by small number of fruits in next year with low total fruit production. As a consequence, the farmers get low income over years. Ethephon application in the form of foliar […]

Abstract A pharmacokinetic study based on single oral administration of Tenofovir disoproxil fumarate 300 mg (tablets) to Argentinean male volunteers under fasting conditions is presented. The obtained values for test and reference products were 238±62 and 261±73 ng mL-1 for Cmax; 1658±466 and 1801±529 ng mL-1 h for AUC0–48h; 1845±579 and 2015±639 ng mL-1 h […]

Abstract Terminalia belerica Roxb. has a long ethnomedicinal tradition of being used as a remedial agent in various diseases. The present study aimed to investigate antioxidant and cytotoxic activity of the methanolic extract of T. belerica fruits. Antioxidant potential of the extract was evaluated by using the 2, 2-diphenyl-1-picrylhydrazyl (DPPH) scavenging assay, nitric oxide scavenging […]